Illumina (ILMN) Insider Sales Reduce Stake, Analysts React

Caroline Francis

Updated on:

Recent filings for Illumina Inc. (NASDAQ: ILMN) reveal substantial insider activity. On November 17, 2025, the company’s 10% owner, ILLUMINA, INC., sold 1,000,000 shares for a total of $79.85 million, at $79.85 per share. After this transaction, the firm retains 3,502,126 shares, valued at roughly $454.02 million, reflecting a significant but measured reduction in its stake.

In addition, Scott Davies purchased 323 shares, generating $39,661 in proceeds, while Director Gottlieb Scott bought 500 shares at $122.13 per share, totaling $61,065, and now holds 12,523 shares worth approximately $1.62 million. These transactions indicate ongoing insider participation alongside strategic divestment by major shareholders.

Analyst Ratings and Coverage Updates

Illumina has seen multiple revisions in analyst coverage recently. Daiwa Securities downgraded ILMN from Outperform to Neutral, reflecting a more cautious view. Similarly, Scotiabank reduced its rating in mid-July from Sector Outperform to Sector Perform. Citigroup maintained its Neutral rating on March 4, 2025, while HSBC Securities downgraded the stock from Buy to Hold on February 28, 2025. These analyst updates suggest a tempered outlook on the stock’s near-term growth potential.

Price Performance Overview

On Tuesday, ILMN stock rose 2.92%, closing at $129.64. Over the last five trading days, shares have gained 6.29%, signaling short-term momentum. Despite this, ILMN has declined 5.37% year-to-date and 2.99% over the past year.

The stock has experienced a 52-week high of $153.06 on January 14, 2025, and a 52-week low of $68.70 on April 9, 2025, highlighting significant price swings and volatility typical of the genomics and biotech sector.

Support and Resistance Levels

Technical analysis identifies key levels for ILMN. Support is currently at $126.60, with a secondary support at $123.57, providing potential buy zones if the stock dips. On the upside, resistance is at $131.57, with a further level at $133.51, indicating potential short-term price targets for bullish movements.

Short Interest Trends

Short interest in ILMN declined slightly as of November 14, 2025, dropping by 0.13 million shares to a total of 6.54 million shares. Previously, on October 15, 2025, short interest stood at 6.68 million shares, representing a 2.06% decline. This modest decrease in short positions suggests a cautious negative sentiment among traders, with some reducing bets against the stock.

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